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What is the sepsis protocol?

What are Sepsis Protocols? A protocol in a medical context refers to a set of rules or a specific plan that doctors and nurses must follow during treatment. Sepsis protocols describe the treatment guidelines that clinicians must follow when assessing and treating patients with sepsis. Sepsis Protocols Save Lives.

What are the 6 essential interventions to treat sepsis?

Sepsis Six

  • Titrate oxygen to a saturation target of 94%
  • Take blood cultures and consider source control.
  • Administer empiric intravenous antibiotics.
  • Measure serial serum lactates.
  • Start intravenous fluid resuscitation.
  • Commence accurate urine output measurement.

What are your chances of surviving sepsis?

As sepsis worsens, blood flow to vital organs, such as your brain, heart and kidneys, becomes impaired. Sepsis may cause abnormal blood clotting that results in small clots or burst blood vessels that damage or destroy tissues. Most people recover from mild sepsis, but the mortality rate for septic shock is about 40%.

How long is a hospital stay with sepsis?

The average length of stay (LOS) for sepsis patients in U.S. hospitals is approximately 75% greater than for most other conditions (5), and the mean LOS in 2013 was reported to dramatically increase with sepsis severity: 4.5 days for sepsis, 6.5 days for severe sepsis, and 16.5 days for septic shock (6).

How do you manage a patient with sepsis?


  1. Antibiotics. Treatment with antibiotics begins as soon as possible.
  2. Intravenous fluids. The use of intravenous fluids begins as soon as possible.
  3. Vasopressors. If your blood pressure remains too low even after receiving intravenous fluids, you may be given a vasopressor medication.

What should you do in the first hour of sepsis?

The Hour-1 interventions are (Levy, Evans & Rhodes, 2018):

  • Measure lactate level (repeat lactate if initial lactate elevated [>2mmol/L]).
  • Obtain blood cultures before administering antibiotics.
  • Administer broad-spectrum antibiotics.
  • Begin rapid administration of 30mL/kg crystalloid for hypotension or lactate ³ 4mmol/L.

Which therapies are required to be administered within 1 hour to treat sepsis?

NICE says that high-risk sepsis patients should get antibiotics and IV fluid treatment within the hour. If it will take more than an hour to get someone to hospital, GPs or ambulance staff can also administer antibiotics.