What is indocyanine green angiography used for?
ICG is used to acquire an angiogram of the choroid. The choroid is the layer of blood vessels and connective tissue between the sclera (white of the eye) and retina. It supplies nutrients to the inner parts of the eye.
When are ICG angiography images taken?
The dye is injected and images are taken rapidly in the beginning. Images are usually taken at intervals at least up to thirty minutes, and perhaps as long as an hour after the injection. ICG angiography is similar to fluorescein angiography.
What are the phases of fluorescein angiography?
Fluorescein angiograms progress through five phases: pre-arterial (choroidal flush), arterial, arteriovenous, venous and late recirculation.
What is indocyanine green dye?
Indocyanine green injection is a medical dye used in tests to help determine the cardiac (heart) output, liver function, and blood flow in the liver. It is also used to help certain parts of the eye to become more visible during medical procedures such as angiography.
What is fluorescein and indocyanine green angiography?
Fluorescein and ICG Angiography are used to image the posterior layers of the eye. Generally it allows the physician an better understanding of the disease process. This imaging procedure is conducted using a small amount of liquid dye that is injecting into a vein, similar to a blood draw with a butterfly needle.
How does indocyanine green work?
ICG absorbs near infra-red, especially light with a wavelength of about 805 nanometers. A laser of that wavelength can penetrate tissue. That means, dying tissue with injected ICG allows an 800 nm to 810 nm laser to heat or overheat the dyed tissue without harming the surrounding tissue.
How would you describe fluorescein angiography?
Fluorescein angiography is an eye test that uses a special dye and camera to look at blood flow in the retina and choroid. These are the two layers in the back of the eye.
What is fluorescein angiography?
Fluorescein angiography looks at the blood flow to your retina and the rest of your eye. Your eye doctor may recommend it for reasons like: To diagnose, confirm, or rule out a retinal disease, including eye melanoma (cancer) To figure out if an eye treatment is working.
What is indocyanine green made from?
Indocyanine Green for injection USP is a sterile, lyophilized green powder containing 25 mg of Indocyanine Green with no more than 5% sodium iodide. It is packaged with Sterile Water for injection, USP used to dissolve the Indocyanine Green. Indocyanine Green for injection USP is to be administered intravenously.
Is indocyanine green nephrotoxic?
The most widely adopted reagent for NIRF in urologic surgery is the fluorescent dye, indocyanine green (ICG). ICG is non-nephrotoxic, excreted exclusively by the liver, with inci- dences of minor and major complications being exceedingly rare [1].
Is indocyanine green a contrast?
Nanoparticles 100 nm in diameter containing indocyanine green (ICG) have been developed as a contrast agent for photoacoustic (PA) imaging based on (photonic explorers for biomedical use by biologically localized embedding PEBBLE) technology using organically modified silicate (ormosil) as a matrix.
What is the CPT code for indocyanine green angiography?
Indocyanine-green angiography (includes multi-frame imaging) with interpretation and report: 92242: Fluorescein angiography and indocyanine-green angiography (includes multiframe imaging) performed at the same patient encounter with interpretation and report, unilateral or bilateral: Other CPT codes related to the CPB: +38900
When to use indocyanine green angiography for retinal neovascularization?
It is generally used in evaluating retinal neovascularization, serous detachment of retinal pigment epithelium, hemorrhagic detachment of retinal pigment epithelium, and retinal hemorrhage. Indocyanine green angiography has been under development for the past 30 years as an imaging method for the choroidal vasculature.
How many patients have been photocoagulated with indocyanine green?
In 50 (39 %) of the patients, indocyanine green angiography provided additional information such that occult choroidal neovascularization could be reclassified as a classic pattern. A total of 12 patients underwent laser photocoagulation based on the indocyanine green videoangiography (ICGA) findings.
Is the use of indocyanine green experimental or investigational?
Aetna considers the use of indocyanine green for sentinel lymph node mapping of other cancers (e.g., bladder, breast, colon, kidney, melanoma, ovary, penis, prostate, and stomach; not an all-inclusive list) experimental and investigational because its effectiveness for these indications has not been established. Background