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What class is an arb?

Valsartan, losartan, irbesartan and other “-sartan” drugs are a class of medicines known as angiotensin II receptor blocker (ARBs) used to treat high blood pressure and heart failure.

What drugs are classified as ARBs?

Examples of ARBs include:

  • Atacand (candesartan)
  • Avapro (irbesartan)
  • Benicar (olmesartan)
  • Cozaar (losartan)
  • Diovan (valsartan)
  • Micardis (telmisartan)
  • Teveten (eprosartan)

Do ARBs block AT2?

Theoretically, the combination of an ACE inhibitor with an ARB should more effectively block Ang II, allow for stimulation of the AT2 receptor, and increase bradykinin levels through reduced degradation and through stimulation of the AT2 receptor.

Do angiotensin blockers lower heart rate?

Losartan is not a beta-blocker, though, like beta blockers, losartan (called an ARB or angiotensin receptor blocker) is also used to treat high blood pressure. ARBs lower blood pressure by blocking the action of a hormone that causes your blood vessels to constrict, while beta blockers reduce how hard your heart beats.

Is amlodipine an ARB?

Amlodipine is an effective antianginal agent, whereas ARBs are not. However, amlodipine is not effective in the treatment of heart failure; ARBs may be useful in this setting. ARBs are also effective in preserving renal function and may provide some protection from restenosis in patients who have had a PCI.

What are examples of ARBs?

Examples of angiotensin II receptor blockers include:

  • Azilsartan (Edarbi)
  • Candesartan (Atacand)
  • Eprosartan.
  • Irbesartan (Avapro)
  • Losartan (Cozaar)
  • Olmesartan (Benicar)
  • Telmisartan (Micardis)
  • Valsartan (Diovan)

Do ARBs block AT1 or AT2?

Angiotensin II, through AT1 receptor stimulation, is a major stress hormone and, because (ARBs) block these receptors, in addition to their eliciting anti-hypertensive effects, may be considered for the treatment of stress-related disorders.

What does the AT2 receptor do?

In the kidney, both the AT1 and AT2 receptors contribute to the regulation of renal hemodynamic and tubular functions. Also, these receptors regulate renal cellular growth and matrix formation. However, AT2 receptor possesses functions that counteract the effects of the AT1 receptor.