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What causes Wagner syndrome?

Wagner syndrome is caused by mutations in the VCAN gene and is inherited in an autosomal dominant manner. Treatment varies depending on the signs and symptoms in each individual and may include the use of glasses or contact lenses and vitreoretinal surgery.

What is optically empty vitreous?

“Optically empty vitreous” means that there are no visible floaters, veils, opacities, or rings suspended within the vitreous gel filling the eye behind its natural lens.

Is Wagners disease hereditary?

Wagner syndrome is a hereditary disorder that causes progressive vision loss. The eye problems that lead to vision loss typically begin in childhood, although the vision impairment might not be immediately apparent.

Is Wagner’s an autoimmune disease?

Granulomatosis with polyangiitis (GPA, formerly called Wegener’s) is a rare disease of uncertain cause. It is the result of inflammation within the tissues called granulomatous inflammation and blood vessel inflammation (“vasculitis”), which can damage organ systems.

What is a lamellar cataract?

Lamellar or zonular cataract is a hereditary cataract that is transmitted in an autosomal dominant mode. The crystalline opacities are located at the level of the primary fibers in the embryonic nucleus. This cataract is usually bilateral and asymmetrical.

Is Wagner’s disease fatal?

Granulomatosis with polyangiitis is a rare type of vasculitis. If only the blood vessels of the respiratory system are affected, the disease is known as ‘limited Granulomatosis with polyangiitis’. Wegener’s granulomatosis may be fatal without prompt medical treatment.

What are the symptoms of Wagner syndrome?

Symptoms of Wagner syndrome 1. The list of signs and symptoms mentioned in various sources for Wagner syndrome 1 includes the 9 symptoms listed below: Progressive vision loss. Empty vitreous cavity. Preretinal avascular membrane.

What are the top 10 autoimmune diseases?

According to The Autoimmune Registry, the top 10 most common autoimmune diseases include: Rheumatoid arthritis. Hashimoto’s autoimmune thyroiditis. Celiac disease. Graves’ disease. Diabetes mellitus, type 1. Vitiligo.

What is Wagner’s disease?

Wagner’s disease. Wagner’s disease is a familial disease of the eye that can cause reduced visual acuity. Wagner’s disease was originally described in 1938.

Is Wegener’s disease fatal?

Wegener’s disease. (Wegener’s disease is an autoimmune disorder where the body attacks the veins and arteries going to and from the kidneys, it is usually fatal in 2 years)