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What are the symptoms of an allergic reaction to sulfa?

If you’re allergic to sulfa drugs or any other medication, you may have one or more of these symptoms:

  • Skin rash or hives.
  • Itchy eyes or skin.
  • Breathing problems.
  • Face swelling.

What is sulfonamide hypersensitivity?

Sulfonamide antimicrobials are commonly reported as causing drug allergy and have been implicated in a variety of hypersensitivity reactions including immediate IgE-mediated reactions, benign T-cell-mediated rashes, and severe cutaneous adverse reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and …

What is hypersensitivity drug reaction?

Drug hypersensitivity reactions (DHR) include allergic, exaggerated pharmacologic, and pseudoallergic reactions to medications that result from an enhanced immunologic or inflammatory response.

Does topiramate have sulfa in it?

A subgroup of the non-antibiotics are simply sulfonamide containing and include sumatriptan, topiramate, zonisamide, ibutilide, sotalol, dapsone and probenecid. This group contains a sulfonamide moiety not directly connected to the benzene ring.

What are side effects of sulfa drugs?

Side Effects of Sulfonamides

  • Skin rash.
  • Itching.
  • Headache.
  • Dizziness.
  • Diarrhea.
  • Tiredness.
  • Nausea or vomiting.
  • Pale skin.

What type of hypersensitivity is sulfa allergy?

Sulfonamide antibiotic reactions encompass the entire spectrum of hypersensitivity reactions (types 1–4). Type 1 hypersensitivity is IgE-mediated and may include an anaphylactic sequelae. Type 2 reactions involve antibody-mediated cytotoxic cellular injury that may result in various cytopenias.

What are Sulpha drugs?

Sulfonamides, or “sulfa drugs,” are a group of medicines used to treat bacterial infections. They may be prescribed to treat urinary tract infections (UTIs), bronchitis, eye infections, bacterial meningitis, pneumonia, ear infections, severe burns, traveler’s diarrhea, and other conditions.

What are examples of hypersensitivity reactions?

Type I hypersensitivity reactions can be seen in bronchial asthma, allergic rhinitis, allergic dermatitis, food allergy, allergic conjunctivitis, and anaphylactic shock. Anaphylaxis is a medical emergency as it can lead to acute, life-threatening respiratory failure. It is an IgE-mediated process.

Can you take topiramate with a sulfa allergy?

Although topiramate is a sulfamate compound, none of these patients had history of hypersensitivity to sulfa drugs and it is not clear whether this reaction may be related to sulfa allergy. Interestingly, I found no reports of use of topiramate in patients with hypersensitivity to sulfa drugs.

Can you be allergic to topiramate?

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

What happens if you have an allergic reaction to sulfa?

This potentially life-threatening reaction causes skin to blister and peel off. Other reactions to sulfa drugs include headache, trouble sleeping, cloudy urine (crystalluria), and low blood counts. Rarely, a severe allergic reaction called anaphylaxis happens. Drugs to Avoid With Sulfa Allergies

What kind of antibiotics can you take with a sulfa allergy?

Sulfonamide antibiotics that can cause a reaction. Antibiotics containing chemicals called sulfonamides can trigger a reaction if you have a sulfa allergy. These antibiotics include combination drugs: Sulfamethoxazole-trimethoprim (Septra, Bactrim) Erythromycin-sulfisoxazole.

Can you take sulfanamide if you are allergic to wine?

An allergy to sulfonamide medications is different from having an adverse reaction to wine or food that contains sulfites. Having a reaction to sulfites in something you eat or drink doesn’t mean you’ll be allergic to sulfonamide medication.

Can a person with sulfa allergy take trimethoprim?

In the majority of cases, a person with a sulfa allergy will have experienced an allergic reaction to one or more of the following antibiotic drugs: Septra (sulfamethoxazole and trimethoprim)