What causes filovirus?
Factors like population growth, encroachment into forested areas, and direct interaction with wildlife (such as bushmeat consumption) may contribute to the introduction of filoviruses into human populations.
Which of the following is an example of a filovirus?
The Filoviridae Family To date, six distinct species of Ebolavirus have been discovered, including the Ebola virus, Sudan virus, Taï Forest virus, Bundibugyo virus, Reston virus, and Bombali virus.
What does the word filovirus mean?
: any of a family (Filoviridae) of single-stranded chiefly filamentous RNA viruses that infect vertebrates and include the Marburg virus and the Ebola viruses.
How does Filoviridae infect the body?
Fatal filovirus infections usually end with high viremia and no evidence of an immune response. In humans and monkeys, infection leads to an extensive disruption of the parafollicular regions in the spleen and lymph nodes that contain the antigen-presenting dendritic cells.
How is Filovirus transmitted?
Filoviruses are believed to be transmitted from wildlife to people through contact with reservoir fruit bats, and through intermediate or amplifying hosts, such as monkeys, great apes, duikers or pigs that have themselves become infected through contact with bat saliva or feces [23,31].
What virus is caused by the filovirus species?
Filoviridae consists of two genera, Marburgvirus and Ebolavirus. The first strain of Marburgvirus was discovered in 1967, when it was transported with imported monkeys to Marburg, Germany, and caused a fatal outbreak.
What is the size of Filovirus?
Filovirus, any virus belonging to the family Filoviridae. Filoviruses have enveloped virions (virus particles) appearing as variably elongated filaments that are about 80 nm (1 nm = 10−9 metre) in diameter and generally between 650 and 1,400 nm in length.
What are the symptoms of Marburg virus?
Nausea, vomiting, chest pain, a sore throat, abdominal pain, and diarrhea may appear. Symptoms become increasingly severe and can include jaundice, inflammation of the pancreas, severe weight loss, delirium, shock, liver failure, massive hemorrhaging, and multi-organ dysfunction.
Is coronavirus a filovirus?
The Novel Coronavirus is different from the Ebola virus. Ebola virus is a bloodborne, highly infectious, enveloped filovirus. In contrast, SARS and MERS are from the same family of coronaviruses and have similar physical and biochemical properties and comparable transmission routes to COVID-19.
Which virus is caused by the filovirus species?
Filoviridae (/ˌfaɪloʊˈvɪrɪdiː/) is a family of single-stranded negative-sense RNA viruses in the order Mononegavirales. Two members of the family that are commonly known are Ebola virus and Marburg virus.
What do paramyxoviruses cause?
A number of important human diseases are caused by paramyxoviruses. These include mumps, as well as measles, which caused around 733,000 deaths in 2000. The human parainfluenza viruses (HPIV) are the second most common causes of respiratory tract disease in infants and children.
How does the host respond to the filovirus?
Filovirus disease is characterized by uncontrolled virus replication and the activation of host responses that contribute to pathogenesis. Underlying these phenomena is the potent suppression of host innate antiviral responses, particularly the type I interferon response, by viral proteins, which allows high levels of viral replication.
What happens if you get a filovirus infection?
Severe infection with filoviruses can lead to viral haemorrhagic fever and other coagulation abnormalities. Filoviruses evade and alter the innate immune response through various mechanisms.
Who was the first person to get filovirus?
The first Filovirus was recognized in 1967 when a number of laboratory workers in Germany and Yugoslavia, who were handling tissues from green monkeys, developed hemorrhagic fever.
Can a filovirid virus spread to a monkey?
Viruses in the family Filoviridae can cause severe hemorrhagic fever in people and nonhuman primates (such as monkeys and gorillas) and may spread in other animals, such as bats. Filoviruses are enveloped in a lipid (fatty) membrane and appear in several shapes.