What should you not take with simvastatin?
Do not use more than 20 mg per day of simvastatin together with amiodarone (Cordarone®), amlodipine (Norvasc®), lomitapide (Juxtapid™), or ranolazine (Ranexa®). When used together with higher doses of simvastatin, these medicines may increase your risk of muscle injury and could result in kidney problems.
What Simvastatin is used for?
Simvastatin belongs to a group of medicines called statins. It’s used to lower cholesterol if you’ve been diagnosed with high blood cholesterol. It’s also taken to prevent heart disease, including heart attacks and strokes.
What is the common name for Simvastatin?
Simvastatin oral tablet is available as a brand-name drug and a generic drug. Brand name: Zocor. Simvastatin comes in two forms: an oral tablet and an oral suspension. Simvastatin oral tablet is used to help lower cholesterol and triglyceride levels.
Are all statins generic?
Pravastatin and fluvastatin have a lower risk of drug interactions because they are not metabolized by cytochrome p450 3A4. Atorvastatin and fluvastatin are considered the most cost-effective statins….What are the differences between statins?
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Can simvastatin affect blood pressure?
In conclusion, simvastatin promotes a significant reduction of BP in patients with hypertension, particularly in patients with higher levels of total cholesterol. This effect may account for a part of the beneficial effects of statins in the prevention of cardiovascular disease.
Is simvastatin a blood thinner?
The short answer is YES, but very little. Cholesterol lowering drugs, often called “statins” are intended to lower an important component of your total blood cholesterol, the LDL or “low density lipoproteins”.
Which is the cheapest statin?
The most expensive statin per 30 tablets was atorvastatin with a mean price of $21.48, and the least expensive statin was simvastatin with a mean price of $5.89.
What is the difference between rosuvastatin and simvastatin?
Aside from being better at lowering so-called “bad” cholesterol levels in the bloodstream, another advantage to rosuvastatin is that it has far fewer negative interactions with other medications than simvastatin, or most other statins, for that matter.
Who is the manufacturer of simvastatin in the US?
Simvastatin was initially marketed by Merck & Co under the trade name Zocor, but is available generically in most countries following the patent expiry. A combination of simvastatin along with ezetimibe is sold under the brand name Vytorin and is jointly marketed by Merck and Schering-Plough.
When did Merck start using simvastatin in medicine?
Simvastatin patented by Merck in 1980 and came into medical use in 1992. It is on the World Health Organization’s List of Essential Medicines, which lists the most effective and safe medicines needed in a health system. It is available as a generic medication.
What kind of fungus is simvastatin made out of?
Simvastatin is made from the fungus Aspergillus terreus. In 2018, it was the tenth most commonly prescribed medication in the United States, with more than 48 million prescriptions.
What are some of the medical uses of simvastatin?
Medical uses. The primary uses of simvastatin are to treat dyslipidemia and to prevent atherosclerosis-related complications such as stroke and heart attacks in those who are at high risk.