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What is a mixed germ cell tumor?

Listen to pronunciation. (mikst jerm sel TOO-mer) A rare type of cancer that is made up of at least two different types of germ cell tumors (tumors that begin in cells that form sperm or eggs). These may include choriocarcinoma, embryonal carcinoma, yolk sac tumor, teratoma, and seminoma.

What are the two types of germ cell tumors?

There are two types of germ cell tumors that start in the gonads, or reproductive organs: seminomas, which are slower-growing, and nonseminomas, which are faster-growing tumors. These germ cell tumors typically form during puberty.

What are the germ cell Tumours?

Germ cell tumors are growths of cells that form from reproductive cells. The tumors may be cancerous or not cancerous. Most germ cell tumors occur in the testicles or the ovaries. Some germ cell tumors occur in other areas of the body, such as the abdomen, brain and chest, though it’s not clear why.

What is the most common type of germ cell tumor?

Teratomas are the most common type of germ cell tumor to develop in extragonadal (not in the ovary or testes) areas. Doctors usually treat teratomas with surgery because chemotherapy doesn’t work in a benign tumor.

What is a mixed tumor?

From Wikipedia, the free encyclopedia. A mixed tumor is a tumor that derives from multiple tissue types. A biplastic tumor or biphasic tumor has two tissue types.

What is a germ cell?

Listen to pronunciation. (jerm sel) A reproductive cell of the body. Germ cells are egg cells in females and sperm cells in males.

Is teratoma germ cell tumor?

Teratomas contain cells from the three germ layers: ectoderm, mesoderm, and endoderm. Teratomas can be malignant or benign, depending on the maturity and other types of cells that may be involved. Teratomas are the most common germ cell tumor found in the ovaries.

Where do germ cell tumors spread?

Germ cell tumors can spread (metastasize) to other parts of the body. The most common sites for metastasis are the lungs, liver, lymph nodes, and central nervous system. Rarely, germ cell tumors can spread to the bone, bone marrow, and other organs.

Is mixed tumor benign or malignant?

8 – 9% of mixed tumors may undergo malignant transformation after 15 – 25 years; the result is an invasive, highly malignant tumor, usually a squamous cell or undifferentiated carcinoma.

Where are mixed tissue tumors commonly found?

The mixed tumor is the most common tumor of the major and minor salivary glands (Box 8-14). The parotid gland accounts for approximately 85% of these tumors, whereas the submandibular gland and the intraoral minor salivary glands account for 8% and 7%, respectively.