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How is SURVANTA administered?

Administer SURVANTA intratracheally by instillation through a 5 French end-hole catheter. Each dose of SURVANTA is 100 mg of phospholipids/kg birth weight (4 mL/kg).

How is surfactant administered?

Methods to deliver surfactant The surfactant is administered via a thin catheter into the trachea in small aliquots, while the baby is spontaneously breathing on CPAP support. In infants 29-32 weeks gestation, LISA may reduce the occurrence of pneumothorax and need for mechanical ventilation.

How is Beractant administered?

Beractant is administered intratracheally. It is delivered directly to the site of action, and only a small amount reaches the systemic circulation. Distribution is improved by positioning the infant to allow gravity to help distribute surfactant to the distal airways.

How do you prepare SURVANTA?

Before administration, SURVANTA should be warmed by standing at room temperature for at least 20 minutes or warmed in the hand for at least 8 minutes. Artificial warming methods should not be used. If a prevention dose is to be given, preparation of SURVANTA should begin before the infant’s birth.

When do you give SURVANTA?

Recommended Dosage To treat infants with RDS confirmed by radiographic and clinical findings, give the first dose of SURVANTA as soon as possible, preferably by 8 hours of age. Four doses of SURVANTA can be administered in the first 48 hours of life. Doses should be given no more frequently than every 6 hours.

How do you administer curosurf?

Administer CUROSURF suspension through the proximal end of the secondary lumen of the endotracheal tube as a single dose, given over 1 minute, and without interrupting mechanical ventilation.

How do you administer CUROSURF?

When do you give survanta?

How do you inject SURVANTA?

First quarter-dose aliquot of SURVANTA suspension:

  1. Position the infant appropriately in one of the four recommended positions.
  2. Insert the 5 -French end-hole catheter into the endotracheal tube.
  3. Gently inject the first quarter-dose aliquot through the catheter over 2-3 seconds.

What is survanta made from?

Beractant, also known by the trade name of Survanta, is a modified bovine pulmonary surfactant containing bovine lung extract (phospholipids, neutral lipids, fatty acids, and bovine surfactant proteins), to which synthetic DPPC, tripalmitin and palmitic acid are added.

Is surfactant a medicine?

Pulmonary surfactant is used as a medication to treat and prevent respiratory distress syndrome in newborn babies. Prevention is generally done in babies born at a gestational age of less than 32 weeks. It is given by the endotracheal tube. Onset of effects is rapid.

How much total surfactant will you give a 1kg baby receiving survanta?

The total dose of SURVANTA is 100 mg of phospholipids/kg birth weight (4 mL/kg) and is divided into 4 quarter-doses, also known as aliquots.

How many milligrams of Survanta per quarter dose?

The total dose of SURVANTA is 100 mg of phospholipids/kg birth weight (4 mL/kg) and is divided into 4 quarter-doses, also known as aliquots. Each of the 4 aliquots is given with the infant in a different position to help evenly distribute SURVANTA throughout the lungs.

How is the endotracheal tube suctioned for Survanta?

At the discretion of the clinician, the endotracheal tube may be suctioned prior to administration. Administration is via a 5 French end-hole catheter into the endotracheal tube with the tip of the catheter protruding just beyond the end of the endotracheal tube above the infant’s carina.

Where is Survanta administered in an animal body?

Animal Metabolism. Survanta is administered directly to the target organ, the lungs, where biophysical effects occur at the alveolar surface. In surfactant-deficient premature rabbits and lambs, alveolar clearance of radio-labelled lipid components of Survanta is rapid.

What kind of drug is Survanta for intratracheal use?

Survanta ® (beractant) Intratracheal Suspension is a sterile, non-pyrogenic pulmonary surfactant intended for intratracheal use only.