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How is a transsphenoidal hypophysectomy performed?

Transsphenoidal hypophysectomy: The pituitary gland is taken out through your nose via the sphenoid sinus, a cavity near the back of your nose. This is often done with the assistance of either a surgical microscope or an endoscopic camera.

What can I expect after transsphenoidal surgery?

It can take up to 6 weeks to fully recover. The cuts the doctor made (incisions) may be sore for about 5 days after surgery. You may also have numbness and shooting pains near your wound, or swelling and bruising around your eyes. As your wound starts to heal, it may start to itch.

What is a transsphenoidal Adenomectomy?

Transsphenoidal adenomectomy is a type of surgery that may be used to remove a tumour (adenoma) of the pituitary gland, which lies at the bottom of the brain.

How is Hypophysectomy done?

To remove the pituitary gland through the nose, surgeons make an incision beneath the upper lip. They will then insert a speculum into the nasal cavity, and remove the pituitary tumor with forceps. Opening the skull works best if tumors have extended above the cavity in which the gland is located.

How long does endonasal surgery take?

For routine cases, surgery often takes two hours from the time anesthesia is administered. More complex cases may take from four to six hours.

Which structures produce and release ADH?

Antidiuretic hormone, also known commonly as arginine vasopressin, is a nine amino acid peptide secreted from the posterior pituitary. Within hypothalamic neurons, the hormone is packaged in secretory vesicles with a carrier protein called neurophysin, and both are released upon hormone secretion.

What is adenohypophysis and Neurohypophysis?

The anterior lobe (adenohypophysis) is derived from oral ectoderm and is epithelial in origin, whereas the posterior lobe (neurohypophysis) derives from the neural ectoderm. The composite nature of the pituitary requires that the neural and oral ectoderm interact physically and developmentally.

How is endoscopic endonasal transsphenoidal surgery performed?

The procedure is performed via an anterior sphenoidotomy. The two main characteristics of the endoscopic approach, when compared with the standard microsurgical operation, arise from the use of the endoscope as a unique optical device and from the absence of a transsphenoidal retractor.

How is the endoscope used in pituitary surgery?

Endoscopic pituitary surgery is done with an instrument called an endoscope. An endoscope is a thin, rigid tube that has a microscope, light, and camera built into it, and it’s usually inserted through the nose. The camera lets your surgeon watch on a television screen while inserting other special instruments through the scope to remove the tumor.

How did endoscopic endonasal surgery revolutionize surgery?

Recently, the development of endoscopic endonasal techniques has revolutionized the surgical strategies for approaching the sella and adjacent areas and increased the development of transsphenoidal surgery.

What are the two types of endoscopic surgery?

Tremendous improvements in the overall quality of the endoscopic equipment permitted the evolution of 2 types of “pure” endoscopic procedures: the ventricular and the endonasal transsphenoidal.